Genomic Newborn Screening for Genetic Errors of Immunity

Ladies and Gentlemen,

The German Society for Immunology (DGFI) Working Group for Clinical Immunology (AKKI) holds its annual meeting 2026 the 15th of September 2026 from 9:30 to 13:30 CEST as part of the 55th Annual Meeting of the DGFI, which takes place at the Technical University of Munich from September 15th to 18th 2026.

On the one hand, this orientation of the AKKI annual meeting takes into account the increasing importance of clinical immunology for scientific immunology. This is because the interest of scientific immunology in clinical immunology has grown, since basic research on human samples due to new analysis technologies now is leading to fascinating insights into human immunology. On the other hand, the interest of therapeutic medicine and clinical immunology into scientific immunology has grown, since new therapeutic options such as small molecules, monoclonal antibodies and CAR-T cells are available. Thus, immune-mediated diseases can be treated, but also numerous immunological main and side effects occur that warrant further research.

This year we are focusing on genomic newborn screening for genetic errors of immunity and are proud to present Stefan Kölker, Heidelberg, and Joshua Milner, New York, as keynote speakers.

We encourage all clinical immunologists, translational, and basic science immunologists to submit their abstracts to fabian.hauck@med.uni-muenchen.de and ricardo.grieshaber@fau.de. Abstract deadline is 31st of May 2026. The five best abstracts will be selected for oral presentation.

 

Please find below the preliminary program:

9:25 – 9:30
“Welcome address and opening remarks”,
Fabian Hauck,
spokesperson AKKI, Department of Pediatrics, Dr. von Hauner Children’s Hospital, University Hospital, Ludwig-Maximilians-Universität, Munich, Germany. fabian.hauck@med.uni-muenchen.de and University Children’s Hospital Heidelberg – Mannheim Ltd., Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany. fabian.hauck@umm.de


9:30 – 10:15

“Genomic newborn screening – A pilot program”,
Stefan Kölker,
Division of Pediatric Neurology and Metabolic Medicine, Center for Child and Adolescent Medicine, University Hospital Heidelberg, Heidleberg, Germany. stefan.koelker@med.uni-heidelberg.de

 

10:15 – 10:45
“Syndromic Inborn Errors of Immunity in TREC-Newborn Screening: 5-year Experience from the German Screening Program”,
Lea Graafen,
Department of Paediatric Oncology, Haematology and Clinical Immunology, University Hospital Düsseldorf, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany. lea.graafen@med.uni-duesseldorft.de

 

10:45 – 10:30
“Artificial thymic organoids discriminate T-cell intrinsic vs. thymic stromal and/or epithelia causes of severe neonatal T-cell deficiency”,
Stine Augustin,
Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité-Universitätsmedizin, Berlin, Corporate Member of Free University and Humboldt University and Berlin Institute of Health, Berlin, Germany. stine.augustin@charite.de

 

10:30 – 11:00
Coffee break


11:00 – 11:45

“Scalable generation and functional classification of genetic variants in inborn errors of immunity to accelerate clinical diagnosis and treatment”,
Joshua Milner,
Department of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA. jdm2249@cumc.columbia.edu

 

11:45 – 12:15
“Allogeneic hematopoietic cell transplantation is curative in CARMIL2 deficiency”,
Johannes Rädler,
Department of Pediatrics, Dr. von Hauner Children’s Hospital, University Hospital, LMU Munich, Munich, Germany. johannes.raedler@med.uni-muenchen.de

 

12:15 – 12:45
“CARD11 gain-of-function myeloid cells drive hemophagocytic lymphohistiocytosis”,
Thomas Magg,
Department of Pediatrics, Dr. von Hauner Children’s Hospital, University Hospital, LMU Munich, Munich, Germany. thomas.magg@med.uni-muenchen.de and University Children’s Hospital Heidelberg – Mannheim Ltd., Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany. thomas.magg@umm.de

 

12:45– 13:15
“Succesfull allogeneic HCT in sFAS gamma/delta T-cell-driven autoimmune encephalitis”,
Yannik Vollmuth,
Department of Pediatrics, Dr. von Hauner Children’s Hospital, University Hospital, LMU Munich, Munich, Germany. yannick.vollmuth@med.uni-muenchen.de

 

Fabian Hauck, MD, PhD
Spokesperson AKKI

The AKKI is grateful to its sponsors as follows:

Gold-Sponsor (≤ 2.500 € + VAT, naming as sponsor in the online program and the welcome adresse of the event, information both during the event, distribution of printed information material to event participant): Pharming, Chiesi

Silver-Sponsor (≤ 1.500€ + VAT, naming as sponsor in the online program and the welcome adresse of the event, distribution of printed information material to event participant): CSL Behring

Bronze Sponsor (≤ 500 € + VAT, naming as sponsor in the online program and the welcome adresse of the event): Takeda, Octapharma